JOB: Postdoctoral Position in Computational Epigenomics?of Aging and Cancer

An opportunity has arisen to join the Computational Systems Epigenomics lab, led by Professor Andrew Teschendorff, based at the Shanghai Institute of Nutrition and Health, which is part of the Chinese Academy of Sciences. Our lab has an interest in elucidating the role of epigenetic changes, notably DNA methylation alterations, in aging and cancer predisposition. The specific role of the postdoc position may include (1) to develop novel computational strategies for cell-type deconvolution of DNA methylation data, (2) develop novel computational strategies for cancer risk prediction from multi-modal single-cell omic data, and (3) develop novel computational strategies for building cell-type specific epigenetic and transcriptomic clocks. Our lab has pioneered many of the existing methods, in 2023 receiving a prestigious Clarivate Highly Cited Researcher Award. We collaborate extensively with leading research groups in the US, China and Europe. Thus, the job is an excellent opportunity for a recent PhD graduate to publish high impact papers and grow their international academic career and reputation in Computational Biology. More details about our research interests and past publications can be found here: https://aet21.github.io

Job requirements: A PhD in Statistical Omics/Bioinformatics/Computational Biology or closely related computational/mathematical discipline. Excellent programming skills in R/BioC and Python. Proficiency in using linux OS.

The post starts in January 2025 and is initially for 2 years, but can be extended for additional years upon satisfactory performance. Initial annual salaries will be on the scale of ~ RMB 500,000. Job comes with additional benefits, including subsidy for meals and accommodation.

If interested, please send a CV and cover letter to andrew@sinh.ac.cn and aeteschendorff21@outlook.com

Positions (of which there are two) will be filled on a first-come first-serve basis.

招聘職位：博士后-衰老和癌癥計(jì)算表觀遺傳學(xué)方向

中國科學(xué)院上海營養(yǎng)與健康研究所Andrew Teschendorff研究員領(lǐng)導(dǎo)的計(jì)算系統(tǒng)表觀遺傳學(xué)研究組誠招博士后。研究組旨在研究和闡明表觀遺傳變化，特別是DNA甲基化改變?cè)谒ダ虾桶┌Y易感性中的作用。該博士后職位的具體職責(zé)可能包括：(1) 開發(fā)用于DNA甲基化數(shù)據(jù)的細(xì)胞類型解卷積的新計(jì)算策略，(2) 開發(fā)用于從多模態(tài)單細(xì)胞組學(xué)數(shù)據(jù)預(yù)測(cè)癌癥風(fēng)險(xiǎn)的新計(jì)算策略，(3)?開發(fā)用于構(gòu)建細(xì)胞類型特異性表觀遺傳學(xué)和轉(zhuǎn)錄組學(xué)時(shí)鐘的新計(jì)算策略。研究組在許多現(xiàn)有方法的開發(fā)和發(fā)展上起到了先鋒作用，Andrew Teschendorff研究員在2023年獲得了享有盛譽(yù)的Clarivate高被引研究人員獎(jiǎng)。研究組與美國、中國和歐洲的研究小組有廣泛的合作，因此，這份工作對(duì)于最近獲得博士學(xué)位的人來說，是發(fā)表高影響力論文并在計(jì)算生物學(xué)領(lǐng)域發(fā)展國際學(xué)術(shù)生涯和建立聲譽(yù)的絕佳機(jī)會(huì)。關(guān)于研究組研究領(lǐng)域和過去發(fā)表的論文，更多細(xì)節(jié)可以參閱研究組網(wǎng)站https://aet21.github.io

應(yīng)聘要求：?擁有統(tǒng)計(jì)組學(xué)/生物信息學(xué)/計(jì)算生物學(xué)或其他密切相關(guān)的計(jì)算/數(shù)學(xué)學(xué)科的博士學(xué)位。在R/BioC和Python方面擁有出色的編程技能。熟練使用Linux操作系統(tǒng)。

該職位預(yù)計(jì)從2025年1月開始，最初工作期為2年，如表現(xiàn)出色可適當(dāng)延長工作年限。初始年薪約為50萬元人民幣，另外包括其它福利，例如餐食和住宿補(bǔ)貼等。

有意應(yīng)聘者，請(qǐng)將簡(jiǎn)歷和求職信發(fā)送至andrew@sinh.ac.cn和aeteschendorff21@outlook.com

該職位招聘人數(shù)共計(jì)2名，招滿為止。